Chelators, a list of medicines for children and adults

Chelators — drugs that are widely used in modern medicine for the purpose of removal from the body of toxic substances.

Belonging to this pharmacological group have a variety of effects: bind toxic substances, strukturiert intestinal contents, prevent the consequences of the reverse casting of toxins from the bloodstream into the intestine. The use of sorbents is shown in the majority of poisonings of exogenous (toxin comes from the external environment) and endogenous (toxin formed in the body) nature.

What are chelators?

Among the chelators include drugs having different structure, but United by a common ability to form complexes with toxic substances and pathogenic microorganisms contained in the stomach or intestine. Medical science distinguishes between 3 groups of assets related to these categories:

  • carbon;
  • silicon;
  • organic.

Carbon enterosorbents have a porous structure, through which are able to bind and securely hold a large number of toxic substances. Silicon kind of drugs well binds toxins, however, due to the smooth surfaces of the structural elements, may not reliably hold them. Therefore, the efficiency of silicon chelators are somewhat lower than carbon.

Organic chelators represent a complex of biopolymers (cellulose, lignin). In addition to the main actions of the drugs in this group have some laxative effect due to the swelling of the elements included in the composition of medicines, and increase stool bulk.

Unlike chelators from sorbents

The term «sorbents» in literal translation sounds like «absorbing». The value is too General to be used for the classification of medicinal substances. In today’s world, the sorbents used for purification of drinking water, air in the breathing apparatus and gas masks, in the manufacture of glass and porcelain. Medical sorbents in powder form can be applied directly to wounds to clean them in a liquid injectable form is administered intravenously or intramuscularly, used as medications for blood purification in filters for hemosorption.

The concept of «treatment» more narrow. This group includes only those medicines that are intended for ingestion. Drugs in this category absorb toxins and bacteria contained exclusively in the gastrointestinal tract of the patient. Enterosorbents — one of the subcategories for a large group of sorbents.

Interesting to know: some substances used for reception through the mouth, at the same time can be used for topical treatment. For example, activated carbon included in the filter to clean the blood.

When you want to apply chelators

The scope of the funds, possessing sorption properties, is quite broad. Drugs of this group are used when:

  • poisoning;
  • need bowel cleansing;
  • allergic reactions;
  • helminthiasis.

In specialized sources present information about the use of sorption means to lose weight. However, the effectiveness of the method remains unproven.


Poisoning is the main indication for prescription of chelators. The medications sorption assign regardless of the route of penetration of toxic substances in the body (through the mouth, through the skin, through the lungs, intravenously). The fact that almost all the toxins, after entering into the bloodstream partially released into the lumen of the intestine, where they are subjected to the action of the drug.

Prolonged uncontrolled intake of medicines can lead to constipation, an imbalance of intestinal flora, flatulence. Therefore, in the treatment of poisoning should obey the duration of therapy. So, for today the most known enterosorbent, activated carbon, the average duration of treatment is 7-10 days. More often, however, the drug overturned in 1-2 days after disappearance of symptoms.

Colon cleanse

For preventive cleansing of the bowel is more often used means of organic nature. As mentioned above, these drugs have the ability not only to bind toxic substances, but also to improve bowel movements, which makes them indispensable. The cleansing of toxins is carried out after a long stay in the zone of chemical contamination, when working in hazardous work, with frequent dysbiosis and functional disorders in the intestine.

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For weight loss

By themselves, the chelators do not affect the amount of fat in the human body. With this purpose it is necessary to use special drugs for weight loss. However, in the complex treatment of obesity, severe sorbent means can really be applied. Their goal is deposition of some nutrients coming from food. Carbohydrates, fats and proteins, once bound by the sorbent, not absorbed into the bloodstream and excreted in unchanged form.

Chelators against allergies

One of the reasons of occurrence of external symptoms of Allergy is the formation in the body of endogenous toxins. The latter, as virtually any toxic substances, partially fall on the mucous membranes of the intestine. The use of chelators can bind and clear the body of the patient these toxins, and allergens trapped in the body through the gastrointestinal tract.


Sorption therapy for helminthiasis is of great therapeutic value. By assigning enterosorbents in the majority of cases it is possible to weaken the effect of intoxication arising from the release into the intestine of waste products of parasites. In addition, sorbents mitigate the consequences of the destruction of the bodies of worms in the treatment of extraintestinal parasitic infestations. Drugs with sorptive properties, must not be used simultaneously with anthelminthic drugs. Otherwise, the effect will be largely neutralized.

Effects on the body

In addition to the direct therapeutic effects, the chelators have a number of indirect effects:

  • prevention of allergic reactions;
  • debridement of ulcers of the gastrointestinal tract;
  • eliminate flatulence;
  • eliminating disbacteriosis;
  • mechanical irritation of the receptors and increased activity of the intestine;
  • reducing the functional load on the kidneys and liver in case of poisoning.

Chelators do not penetrate into the bloodstream and have systemic effects. Therefore, the number of side effects is minimal. Prolonged use of this group of funds may develop phenomena of increased gas formation, dysbiosis, in some cases, constipation. In addition, you should consider individual reactions of intolerance to the components included in the composition of a drug. If any of the described phenomena should reduce the dose or completely abandon its use.

List of drugs for an adult person

The best drugs are chelators that are most commonly used today, listed below:

Activated carbon

Produced by special processing of wood or coal, has a porous structure, high adsorption capacity. Coal is produced in the form of black tablets, granules or powder. Tablets take by mouth 2-4 times a day, the rate for 7-14. The calculation of the dose depends on body weight of the patient. Average therapeutic dosage is 1 tablet per 10 kg of weight. The drug in the granules is assigned 1 packet 3 times a day. This dosage form has a higher capacity than the preformed kind of medication.

Important: chelators can be taken simultaneously with other medications, as it greatly reduces the effect last!

Powdered coal can also be used for intake (20-30 g per reception). More often, however, this form of the drug is used for the preparation of washing solutions. A suspension consisting of coal powder, tannin and magnesium oxide (2:1:1) washed stomach in acute poisoning.

Activated charcoal is contraindicated in gastrointestinal bleeding, individual intolerance. During treatment, the patient chair becomes black. This is no reason for refusing therapy. Prolonged use of the drug causes the development of constipation, flatulence, of dysbiosis.


The drug is based on silicon, which can be used not only for intake, but topically for the treatment of purulent wounds, burns. Has no age restrictions, can be used from birth. Has no effect during pregnancy, breast-feeding. Not desirable long courses. Inside applied in the form of an aqueous slurry, to prepare which it is necessary to dissolve the remedy in half a glass of warm water. Dosing of medication is necessary, on the basis of 0.1 gram per kilogram of body weight of the patient. For the day takes 3-4 hours. Each dose suspension prepared immediately before use.

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Treatment polisorba in the intestinal infection is 3-5 days, and chronic Allergy treatment rates for 12-15 days, kidney failure is the basis for imposition of a 25-day courses of therapy. Contraindicated in peptic ulcer disease, intestinal bleeding, individual intolerance.


Silicon enterosorbent. Available in bags of 3 grams. In long-term care becomes the cause of constipation and the formation of fecal stones. Often prescribed for acute diarrhea. Adult dose of the drug in this state is 6 sachets a day, in all other cases — 3 sachets per day. In appointing pregnant and lactating women correction dosing is not required. Substance contained in the product not penetrate into the systemic circulation and breast milk.

To accept smektu needed in the form of aqueous slurry. The solution is prepared before use, for which the contents of the packet dissolved in ½ Cup warm drinking water. The remedy is contraindicated in chronic constipation, as well as other conditions that are a contraindication to the use of the above drugs. The course of treatment until symptoms of diarrhea.


White or almost transparent paste, odorless. Not used in intestinal atony. Adults means take 3 times a day, at 1.5 tablespoons per reception. Pasta mixed in a volume of water three times the quantity of the drug. The total number of medications patients receive in 24 hours should not exceed 67-68 grams.

The course of treatment with enterosgel in acute conditions is 3-5 days. Make the tool you need in 2 hours after taking other medications or food. To prevent intoxications of an industrial nature course extend up to 7-10 days, but the dosage is adjusted and is 2 packets per day.

Contraindications do not differ from those for other sorbents.

Lignin (polyphepan)

Available in the form of hydrolyzed powder. Can disrupt the absorption in the small intestine of vitamins, if you use more than 20-25 days in a row. Dosage adults — 0.5 gram per kilogram of body weight. The resulting amount of substance is divided into 3-4 reception. Tool take, dissolving in a small volume of water. In acute poisoning the course is 3-5 days, chronic — 2 weeks. Re-treatment with lignin must not be earlier than 14 days after the end of the first course of therapy. The antacid is contraindicated in gastritis, atony of the intestine, bleeding in the digestive tract.


The drug is available in tablet form and includes lactulose and lignin. Not used in bowel obstruction, galactosemia, bleeding, atony of the intestine. Like other intestinal adsorbents during long courses of therapy have a negative effect on the internal microflora. Can provoke abdominal pain.

The dose for adults is 3 tablets 3 times a day. It is necessary to observe the time interval between treatment by the adsorbent and the intake of other drugs, foods, supplements. Children assigned to the reception year to 3 years: ½ tablet once. 3 — 12 years: 1 tablet. Over 12 years 2-3 tablets.


White or yellowish hygroscopic powder, intended for the manufacture of an aqueous solution. Not recommended for use during pregnancy and lactation, as reliable data on its safety to the fetus or newborn, breastfeeding, no. If necessary, detoxification in pregnant women is better to choose other drugs to cleanse the body.

To retrieve a single portion of medicine povidone diluted to 5 grams of composition per 100 ml of water. Adults should take 100 ml 3 times per day. The treatment course is 3-7 days. The resulting solution can be mixed with fruit juices or a syrup. Store it in the refrigerator no more than 3 days. Safety of use in children have not been confirmed. Contraindications include bleeding in the brain, bronchial asthma, acute nephritis, renal and cardiovascular failure.

Use adsorbents

The drug, active substance is povidone. Indications, contraindications, dosage and frequency of application are similar to those of povidone.

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List of chelators for kids

In General, a list of medicines for children differs from that for patients adulthood. Are the same indications, contraindications, side effects. The differences are in the dosage of medicines and the multiplicity of their admission.


The child’s weight, kg The amount of drug in 1 reception, g The amount of water, ml
Less than 10 0,5 30
11-20 0,8 50
21-30 1 70
31-40 2 80
41-60 2,5 100
More than 60 3-4 150

In childhood silica (POLYSORB) is dosed in accordance with the data indicated in the table. These doses are calculated for 1 admission tools. Total for the day should be 3 doses. The course of treatment is 3 days in intestinal infection 2 weeks for allergies.

Activated carbon

The dosage and frequency of intake of coal in Pediatrics is the same as in any other branches of medicine. The dose in 1 reception is calculated on the known principle of 1 tablet per 10 kg of patient weight. For ease of use in pediatric patients tablet allowed to shred, stir in the water and give the child to drink the medicine in the form of an aqueous suspension. The course of treatment — 7-14 days. With the disappearance of symptoms can reduce treatment time.


Profuse diarrhea in children is the indication for prescription of smecta in conjunction with the activities aimed at rehydration. Children under 1 year preparation give 1 packet a day, in 1-2 years the dose should not exceed two packs. Since 2 years of age, the child can receive adult dose (3 packets per day). The course of treatment until symptoms of diarrhea.

Important: in the treatment of smektoj infants 1 package of the drug divided into 3 doses. The medicine be mixed with milk or added to cereals and mashed potatoes, used for food.


Infants enterosgel give 0.5 teaspoon 6 times per day. The drug can be mixed with milk or water. Children from one year to 5 years, increase the dose to 0.5 tablespoons. Specified number means take 3 times a day. At the age of 5-14 years, the dose is 1 tablespoon 3 times a day. Further, the dosage corresponds to that for adult patients. Course duration — 3-5 days.

Polifepan (lignin)

Children over 7 years of lignin give 1 tablespoon 3 times per day. At the age of 1-7 years should dose the drug is 1 dessert spoon. Infants — 1 teaspoon. The treatment continues for 3-5 days.


The group of chelators is an excellent way to detoxify the body, cleanse the intestines. Also the drugs in this group have established ourselves as a substance has been used successfully in the treatment of helminthiasis, such as weight loss, allergic reactions.

Drugs that have the ability to settle on yourself and rid the body of toxic components, practically not absorbed in the intestine and do not have systemic action. Therefore, their application is relatively safe even in children. Despite this, the sorbents require caution. Their long-term uncontrolled use can cause constipation, vitamin deficiencies, exacerbation of other illnesses due to leveling actions taken simultaneously with the sorbent of drugs.

Take chelators are required in accordance with the indications for use. Better if you need the drug and the dosage regimen will be picked up by a competent expert. Only in this way can guarantee the successful completion of therapy in the shortest possible time.