Minirin enuresis in children and adults: when used

Use drugs «Minirin» for enuresis in adults and children, to reduce the amount of urine that exceeds the norm because of disorders of the urinary system. Often appointed to this medication, to reduce nocturnal polyuria but also to eliminate other problems associated with incontinence. Medicine «Minirin» is assigned to an expert individual for each patient, depending on patient age and the complexity of his condition. Self described tool increases the risk of undesirable consequences.

Form release and storage

Pharmaceutical preparation «Minirin» is available in the form of tablets, which are oval or round in shape. Pills placed in plastic vials to 30 PCs. Each bottle has a screw cap with child protection and is in a cardboard box with instructions for use inside. Store medication must temperature, which must not exceed 25 degrees Celsius in a place inaccessible to small children, and which does not penetrate direct sunlight. Released medication is a doctor’s prescription and subject to the recommendations for storage its shelf life is 3 years.

When is used?

Assigned medicine «Minirin» for the following pathologies:

  • nocturnal polyuria;
  • the syndrome of diabetes insipidus;
  • primary nocturnal enuresis.

Part medications

The composition of each tablet «Minirin» as the active ingredient is desmopressin. Additional elements of the drug are:

  • milk sugar;
  • food emulsifier Е572;
  • starch from potatoes;
  • povidone.

The use of Minirin for enuresis in children and adults

Often this disease, as primary enuresis occurs in childhood and is defined as incontinence of urine at night during sleep, when the child is not awaked with a full bladder. Sometimes secondary bedwetting, which occurs as a result of various congenital and acquired pathologies and may occur not only during sleep but also during the day. Drug «Minirin» is used for the treatment of primary enuresis in both adults and children. Start taking medication is the minimum dose which is 0.1 mg and if the desired effect is not forthcoming, then the dosage may be increased to 0.4 mg, but only 1 time in 7 days. You need to take medicine before bedtime and limit the amount of fluid intake in the evening. Therapeutic course is 90 days and, if necessary, can be increased, but only at the discretion of the attending doctor and after a week break.

READ  BCG therapy for bladder cancer: mechanism of action

Before proceeding to the treatment of nocturnal polyuria (profuse urination) in patients over 65 years of age «Minirena», it is necessary to conduct laboratory tests for determination of the amount of sodium in the blood serum. Studies of the sodium level will be required after 3 receptions pharmaceuticals and after each increase in dosage. Adults take «Minirin» once a day before bedtime to 0.2 mg and, if necessary, may increase dosage to 0.1 mg, bringing it up to a maximum dose of 0.4 mg.


If you use drugs «Minirin» to exceed the given dose, patients with enuresis threatened an overdose, which increases the duration of the drug and increases the risk of swelling and cramps. In addition, misuse of a medicinal product, namely a significant excess of the assigned doses can decrease blood levels of sodium, then the patient will need to stop using the medications, to cancel the restriction on the fluid intake and spend the infusion of sodium chloride solution. If the lock fluid pronounced, plus to this treatment, you need to add pharmaceutical product «Furosemide».

Drug interactions

Before proceeding to the treatment of enuresis «Minirena», you should consult with your doctor about combining it with other medicines. For instance, desmopressin, which acts as an active component «Minirin», able to amplify the effect of hypertensive agents, so patients who have been previously appointed, should take into account this interaction. In addition, concomitant use of desmopressin and non-steroidal drugs anti-inflammatory action increases the risk of side effects. In combination «Minirin» with «Indomethacin» increases the duration of action of the active substances of the first drug. If taken together the described remedy enuresis antidiarrheal «Loperamide» that may increase the concentration of desmopressin in the blood in 3 times, and it is dangerous to water retention and reducing the level of sodium in the body.

READ  Operations on the renal pelvis: types, methods, diagnosis


Before therapy enuresis medication «Minirin», you need to make sure that the patient no diseases such as:

  • dysfunction of the cardiac muscle;
  • violation of salt metabolism in the body;
  • pathologically enhanced thirst, both ordinary and psychogenic;
  • increased individual sensitivity to components of the medication;
  • low levels of Na in the blood;
  • replacement by connective tissue of the bladder;
  • missing number or lactose intolerance;
  • renal dysfunction.

It is not recommended to take the medication «Minirin» for children up to 4 years, as well as during pregnancy and lactation. With increased caution should be pills higher risk of intracranial pressure, patients older than 65 years (because of the increased likelihood of side effects). If there is one of these diseases, before taking medication you need to consult with an expert.

Pregnancy and lactation

When carrying a child to take the drug «Minirin» only when the likely benefits to the expectant mother greatly outweighs the potential risks. According to studies, the number of the active component of the described medicament into the body of the baby with mother’s milk in treatment «Minirena», many times less than that which may have an impact on the volume of urine formed.

Side effects

When using from enuresis medicines «Minirin» you may experience the following undesirable phenomena:

  • headache;
  • nosebleeds;
  • felt sick;
  • retching;
  • excessive accumulation of fluid in the tissues;
  • congestion of the nasal cavity;
  • the increase of body weight;
  • cramps;
  • dryness in the mouth;
  • allergic reactions.

Some analogues

In case of impossibility to use in enuresis «Minirin» a doctor can prescribe the patient the same composition of the medicine. Among the analogues described medicines include:

  • «Adiuretinom»;
  • «Waterin-Desmopressin»;
  • «Adiuretinom SD»;
  • «NOREM»;
  • «APO-Desmopressin»;
  • «Amount»;
  • «Nativa»;
  • «Precinct»;
  • «Nativ-Desmopressin».

The ability to control and transport mechanisms

Today, research data on the influence of medication «Minirin» for working with machinery and ability to control the vehicle missing. However, it is worth considering that in the process of therapy data drug there is a risk of side effects such as dizziness and pain in the head that could adversely affect the patient’s response in the management of transport and mechanisms requiring greater attention.

READ  Smear from the urethra in men: how to pass, preparation, decoding

Special instructions

Pharmaceutical agent «Minirin» has some of the features in the application. First of all, keep in mind that this drug must be carefully used elderly patients by increasing the risk of hyponatremia, so the treatment of enuresis in patients over 65 years old should be under regular supervision by specialists. In addition, control over the process of therapy should take place in kids, adolescents and patients having an increased risk of ICP.

To avoid side effects in the process of taking «Minirin» is necessary to avoid drinking fluids for an hour before applying the medication and for 8 hours after drinking a dose of patients with primary nocturnal enuresis. You should not drink the described medications to patients of advanced age, whose blood sodium is much below normal. If the therapy has any infectious lesion, an inflammatory disease of the stomach and small intestine or fever, the acceptance of medication you want to suspend.

In summarizing it should be emphasized that for best absorption components «Minirin», he has to take it 30-40 minutes before a meal or 2 hours after it. Dosage should be adjusted to each patient individually and treatment should begin with minimal doses, with a possible subsequent increase. During the first 2-3 days of reception of the described pharmaceuticals from enuresis may experience swelling of the face and small fluid retention, which indicates excessive dosage.