Fluconazole cystitis: how to take, contraindications

To combat cystitis pharmacy network offer an array of different drugs, particularly fluconazole. This pharmaceutical agent belongs to a group of antibiotics and has a strong antifungal effect. Fluconazole shows good results in the treatment of cystitis, microbial type, but it should be applied exclusively by the doctor’s recommendations to minimize the risk of possible side effects.

The composition and form of issue

In drugstores it is possible to meet the described drug in the following forms, which release the producers:

  • powder;
  • tablets;
  • solution for injections;
  • capsules.

Components of medicines are auxiliary components such as magnesium stearate, povidone, lactose, gelatin, colorant E131, starch derived from corn, titanium dioxide. The active substance acts as fluconazole, which is detrimental effect on the fungal cells. A medicine Packed in blister packs, each with 7 capsules (50 mg) and one capsule, if the current component contains 150 mg. To each package instruction manual.

Pharmacological properties and mechanism of action

The antifungal agent fluconazole has a specific effect on the body, which is the ability of inhibition of enzyme activity, which are important for fungi. In addition, the drug is actively preventing the conversion of lanosterol to ergosterol and disrupts development and cellular growth of the fungus. Thanks to its properties, fluconazole can accumulate in the blood, in the skin and internal organs in the concentration necessary for the destruction of fungi. The described pharmaceutical agent has a high absorption and be taken regardless of food.

When to take the drug?

Antifungal medication is assigned for the following pathologies:

  • fungal cystitis;
  • cryptococcosis;
  • in inflammatory process after surgery;
  • as a preventive measure when having low immunity;
  • after the radiation therapy;
  • thrush;
  • after treatment with immunosuppressants.

Dosage of Fluconazole and the use of cystitis

If the patient was diagnosed with a bladder infection, it the relevant professionals can prescribe fluconazole. To treat cystitis data drug need, strictly observing dosage. Thus, the daily dose should not exceed 200 mg. to Use the medication should at one time, in the case of scheduled injections should proceed with caution and enter the medication, do not exceed the rate of 5-10 ml/min.

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Cystitis without complications in adults relies knocking take 50 mg of drug for 7-28 days. If urinary tract infection is acute or chronic form, the daily dosage should be on average 350 mg and taken within 2 months. In the treatment of fungal cystitis dosage is almost always stable and is 150 mg per day.

Special groups of patients

Using the described medicament for the treatment of inflammatory process in the bladder, it is necessary to consider the restrictions for some patients. For example, take kids fluconazole to 3 years is not recommended, and children older appointed dose to match 2-4 mg per 1 kg of weight of the child. From the therapy of cystitis and other illnesses, which are susceptible to this antifungal drug, in the period of carrying a child are advised to refrain. Specialists can prescribe fluconazole pregnant, but on the condition that the infection threatens the life of the mother. The drug is contraindicated in lactation, as the concentration of the active component in milk and in plasma are the same.


Before taking fluconazole for the treatment of inflammation of urinary bladder, you should be familiar with its contraindications, in order to protect themselves from the risk of serious complications. Thus, it is not recommended to drink the medicine the children up to 3 years, pregnant and lactation period. Pharmaceutical contraindicated with hypersensitivity to components of drug. Should abandon treatment of cystitis the medications for kidney and liver failure.

Side effects

Failure to observe the indicated dosages and, in the case of the use of «Fluconazole» at current contraindications, the patient threatens to experience the following side effects:

  • yellowness of sclera of eyes and skin;
  • pain in the abdomen;
  • felt sick;
  • flatulence;
  • poor appetite;
  • diarrhea;
  • increases the level of cholesterol in the blood;
  • dizziness;
  • cramps;
  • rashes on the dermis of the skin and mucous membranes;
  • swelling of skin tissue, the skin.
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Symptoms of overdose

In each package of «Fluconazole» without exception, is the statement in which specified doses, in addition, to obtain information about the required dosages can be of the specialist. Ignoring the recommendations of the medical profession, there is a risk of overdose symptoms, observing which stop taking the medicines. In most cases, symptoms go away on their own, but if the symptoms persist and the patient gets worse, then you need to seek help to the doctor. To testify of overdosage may be nausea, a gag reflex, diarrhea, and cramps.

It is useful to provide the patient independently before arrival of physicians. This should reduce the penetration of the component medications in the body by gastric lavage. Effectively this event for the first time 4 hours after onset of symptoms. In addition, doctors recommend to make absorbent products, for example, the activated coal from calculation 1 tablet on 10 kg of body weight of the patient.

Drug interactions

It is important in the treatment of cystitis «Fluconazole» to take into account its interactions with other medicines. For example, it is not recommended to take this tool with «Warfarin», as there is a risk of an increase in prothrombin time, which is also possible in the complex treatment described medication with coumarin anticoagulants. May develop hypoglycemia if you take fluconazole together with hypoglycemic agents patients with diabetes mellitus.

There is no benefit of simultaneous administration of the drug rifabutin, as there have been cases of diseases of the choroid eyeball. May increase plasma concentration of the active ingredient fluconazole, if taken in tandem with hydrochlorothiazide. Increases the concentration of tacrolimus in a joint use with fluconazole and increases the risk of nephrotoxicity.

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Special instructions

To treat a bladder infection drug fluconazole needs to full recovery undertreated form of cystitis leads to recurrence of the disease. In the process of therapy it is important to monitor blood parameters and to monitor the health of the kidneys and liver. If there are failures in the functioning of these bodies, it is necessary to stop further use of the described medication. Patients with AIDS have increased susceptibility to the formation of severe reactions on the skin of the skin, therefore, the appearance of a skin rash, hives after the use of the described pharmaceutical of the drug, followed by a reception stop medication.

Some analogues

If the treatment of cystitis «Fluconazole» it is impossible, physicians administered its analogues. Pharmacy chains offer similar in composition preparations and the most popular and effective are: «Nofunc», «Glucose», «Diflazon», «Mycomax,» «Proconsul», «Diflucan» or «Mikoni». In addition to these medicines, doctors prescribe «Flucostat», «Fluorous», «Ziskin», «Fluconazol» or «»Forkan». Should bear in mind that each drug has a specific treatment plan, you must stipulate with your doctor.