Diuretics in case of poisoning: treatment, possible complications

In severe poisoning of the body resort to diuretic drugs. Diuretics in cases of poisoning effectively used in medical practice. Along with this, doctors strongly warn to use a diuretic without proper appointment and control of the attending physician.

Poisoning and diuretics

Diuretics can be used while intoxication to eliminate toxins from the blood. To their treatment during the poisoning of water-soluble toxic substances. These include:

  • alcoholic beverages;
  • heavy metals and their salts;
  • drugs short and medium periods of exposure on the body;
  • the inhibitory (delaying) of the substance;
  • drugs («Morphine», «Diphenhydramine», «Quinine»);
  • different elements synthesized from the body renal organs.

Forced diuresis

Forced diuresis is an effective way to actively remove the toxins with the help of diuretics that are performed by physicians in a hospital. The meaning of this technique is put into the mix of hydration (filling with water) and dehydration (dehydration) with minimal changes in blood volume and fluid and electrolyte exchanges. Diuretics help to achieve an increase in the filtration ability of the kidneys to effectively eliminate toxic substances in the body. They carry most of the load. Diuretics withdrawn poisonous components from the human body along with urine.

Maintain hydration includes providing an alkaline reaction in the urine, and simultaneous administration of osmotic diuretics. This procedure is used in poisoning with medical drugs. With forced diuresis effortlessly eliminated elements soluble in water. Diuretics in this method lose efficiency due to transition of a part of the toxins from the outer shell inside of the cell with time. As a consequence, the method should be carried out with the use of diuretics in acute poisoning currents as soon as possible. Positive results depend on the degree of intoxication and functionality of the renal organs of the patient.

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Contraindications

Contra-indications for forced diuresis are: renal insufficiency, cardiac insufficiency and a sustained collapse, expressed shock necardiogenny swelling of the lungs and swelling of the brain. People older than 50 years because of violations of filtration of the kidneys injections of diuretics does not always show effectiveness. Intolerance to the components of diuretics.

Methods of treatment

The implementation of forced diuresis simple and affordable to perform. In the initial stages of poisoning (mild intoxication without vomiting) increase the volume of urine provoked by active fractional consumption of the alkaline liquid: hour dose divided into several doses and taken every 20 minutes. After half an hour, an increase of urine formation. In severe forms of poisoning method of forced diuresis is carried out with intravenous diuretics. Treatment is carried out in 3 stages:

  1. Check your body’s response to the water load and stimulation increase in bladder volume over 4 hours intravenously way 25% of the planned volume of fluid and diuretics («Mannitol», «Furosemide»). At the end of the stage is resumed, the balance between input and output fluid.
  2. Direct hydration: 4 hours, enter 50% of the intended volume of fluid, repeated injections diuretics. For alkaline urine using a solution of sodium bicarbonate.
  3. Corrective work to restore water and salt balance: enter 25% of the remaining liquid, while controlling the composition of salts in the blood. Diuretics are not used.

Possible complications

Complications during the application of diuretics in a forced diuresis are in rare cases. Diuretics in this method provoke the excretion of electrolyte chemicals, which is subject to adjustments. However, an osmotic diuretic, used in this methodology can result in the development of acute left ventricular failure or pulmonary edema.

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