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31 rows · Spanish actor Pablo Pineda, the first European with Down syndrome to complete a .

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People with Down’s syndrome have a high frequency of leukopenia, idiopathic macrocytosis, and mild polycythemia, often without underlying disease In one observational study, approximately two thirds of people with Down’s syndrome had an increased mean corpuscular volume and one third had mild leukopenia None the less, healthcare professionals must have a high index of suspicion for .

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The occurrence of Alzheimer's disease among persons with Down syndrome has caused a great deal of concern for families and care providers of adults with Down syndrome. As discussed by others, research has found that all adults with Down syndrome over the age of 40 develop plaques and tangles in their brains similar to those seen in persons with Alzheimer's disease.


Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. People with Down syndrome are born with an extra copy of chromosome 21, which carries the APP gene. This gene produces a specific protein called amyloid precursor protein (APP). In recent years, Down syndrome has become more common, and children with Down syndrome are living longer. Read below for recent statistics on Down syndrome in the United States. Occurrence of Down syndrome in the United States. Babies: Down syndrome continues to .
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Adulthood. Many adults with Down’s syndrome are now leaving home, living independently with varying degrees of support, holding down jobs, forming relationships and generally getting the most out of life.

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