Zovirax: instructions for use, ointment and tablet, counterparts.

Zovirax: instructions for use, method of issuance and analogues

Drug Zovirax is available in several dosage forms cream for external use, tablets for oral administration, the lyophilisate for preparation of injection and eye ointment. The tool has a antiviral action, is an immunomodulator. Usage instructions ointment Zovirax States that the drug is used for the treatment of viral infections in adults and children. In the composition the main active ingredient of acyclovir, has biological activity against herpes virus. Consider the correct use of medication, as well as deal with analogues of Zovirax for herpes.

  • Pharmaceutical form and composition
  • The principle of action and indications
  • Contraindications and side effects
  • Usage instructions
  • Pills
  • Forms for outdoor use
  • Injectable form
  • Analogues Of Zovirax

Pharmaceutical form and composition

Therapeutic effect provides ingredient aciclovir, which is contained in all dosage forms drug. Each tablet is 0.2 grams of the active ingredient. Additional substances include lactose monohydrate, povidone K30, magnesium stearate, microcrystalline cellulose.

The cream outdoor use contains 0.05 g of acyclovir. Auxiliary components white paraffin, Dimethicone, propylene glycol, macrogol stearate, glycerol, sterile water, liquid paraffin, magnesium lauryl sulfate. In eye ointments present 0,03 g of active antiviral substances, and injections of 0,25 g.

Zovirax is the antiviral agent, is a synthetic analogue of purine nucleoside which has the ability to block the replication of herpes simplex virus of any type. The maximum effect observed against the virus of the first type.

Dosage forms:

  • Cream for local use. The consistency a homogeneous, white color. In total, the percentage of the active component of the total funds of 5%. Tubes are available at a dosage of 10, 2 and 2, 5 g;
  • Pills Zovirax for internal use. The shape is round, color white. They are Packed in blisters, which are in a cardboard bundle;
  • Zovirax ointment – a oily substance smooth. The smell of the unexpressed, the concentration of active component 3%. One tube contains 4.5 g of drug;
  • Form for intravenous administration. Sold in bottles containing powder for preparation of solution – injected method.

Drug Zovirax is not available in capsule form, in powder, syrup and lozenges.

The principle of action and indications

 

Acyclovir is a substance with high antiviral activity. The maximum effect was observed against herpes virus of the first type. Pharmacological effects of the drug on viral infection vysokoizbiratelnoy. Timidinkinaza cells that are infected with HSV transformerait molecules of acyclovir to the monophosphate, it occurs after sequential transformation into a diphosphate and triphosphate.

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When the triphosphate is included in the DNA chain of the virus, there is breakage in the chain, resulting in block the reproduction of viral DNA. In patients on the background of pronounced immunodeficiency, prolonged or repeated courses of therapy with Zovirax contribute to the development of resistant strains. The majority of strains that have a low sensitivity to the active component notes low content of thymidine kinase.

Indications for use:

  • To prevent the development of cytomegalovirus infection in children who underwent a bone marrow transplant. This files most often recommended intravenous.
  • Treatment of viral lesions of Varicella Zoster (shingles, chickenpox).
  • Therapy of infectious lesions of the skin and mucous membranes, the background activity of the herpes virus of any type, including genital form of herpes in adults, and primary and recurrent viruses.
  • As the prevention of recurrent activity of the virus in adult patients and in children with immunodeficiency. In this case, you need to take the pill.
  • The viral form of keratitis (eye ointment is prescribed).
  • When the domestic application of active component is only partially absorbed in the gastrointestinal tract. On the background of prolonged use of the cream there is a slight systemic absorption. Tools Zovirax local action can be used at any age. But the therapy babies up to one year only after consultation with the doctor. Tablets are not recommended for use by children under the age of three.

    Contraindications and side effects

    The drug has few contraindications. Should not be prescribed to children and adults with any form of issue, if a history of allergic reaction to acyclovir any other substances present in the composition. Pills are not prescribed for renal failure patients. Injectable form is used with caution for violation of kidney function, neurological disorders, during pregnancy.

    Important: during the use of ophthalmic ointment Zovirax is strictly forbidden to wear contact lenses.

    The use of eye ointments or outdoor cream rarely leads to the development of negative phenomena. The cream may trigger an allergic reaction, dermatitis, angioedema. Side effects of eye ointment: temporary burning, blepharitis, conjunctivitis, keratopathy point (spontaneously, symptomatic treatment is not required, the drug is not canceled).

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    Pills and injections lead to a systemic phenomena:

  • Disorders of the digestive tract, manifested by nausea, loose stools, vomiting, pain in epigastric region;
  • Leukopenia, anemia;
  • Allergic reaction: fever, rash, itching of the skin, angioneurotic edema, urticaria;
  • Violations kidney function;
  • Increasing the concentration of bilirubin;
  • Loss of hair;
  • Confusion, tremor of limbs, sleep disorder, hallucinations, headache.
  • In the presence of negative systemic phenomena requires correction medications. The patient is administered an analogue of Zovirax.

    Usage instructions

    Regardless of the dosage form of the drug in the package there is a paper version of the instructions for use. It specifies the basic information regarding indications, side effects, dosages and frequency of application. Also highlights the situation when the drug is contraindicated.

    Pills

    Instructions for use Zovirax tablets indicates that the means , washed down with copious amounts of clear liquids. The tablets are swallowed whole. You can not break, chew, or to grind any other way. Drink the medicine during the meal.

    Method of application:

  • On the background of diseases provoked by Varicella Zoster, take one capsule every 4 hours. The rate of application per day – 5 times. The duration of the therapeutic course of five days. In severe infections the duration of therapy increases.
  • As prophylaxis take 4 times daily 1 tablet. Sometimes prescribe a three – fold use- one pill three times or double use – 1 or 2 tablets twice a day.
  • For treatment of varicella tablets are taken 4 times a day. Children age group 3 to 6 years appoint 0,4 g (dosage per application). A child older than 6 years of age give 0.8 g Dose due to weight and age: child’s weight multiplied by 20 mg maximum dosage a day not more than 0.8 g Treatment – five days.
  • Worth knowing: in the treatment of varicella or herpes zoster in an adult administered 0.8 g per day. The pill 4 times to 0.2 g in one application. The course of therapy is 7 days.

    Forms for outdoor use

    Eye ointment into the conjunctival SAC of the strip 1, see Frequency of use – up to five times a day. After recovery to level the negative symptoms, the therapy continues for three more days.

    The cream is applied with clean hands or a cotton pad on the affected area. To lubricate the affected areas have up to five times a day. Duration of treatment course – at least 4 days. If after 4-5 days of treatment improvement is observed, the tool is allowed to use 10 days. Longer treatment only after consultation with a medical specialist.

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    Injectable form

    The drug is injected slowly over one hour. The lyophilisate was dissolved in physiological solution, glucose or sterile water for injections. The dose is adjusted individually. In children the dosage due to weight. Frequency of administration and duration of treatment depend on the specific pathology.

    Analogues Of Zovirax

    Price of Zovirax varies from 10 to 13$. But the Zovirax is there a cheaper analogues: Cyclovir, Virolex, Herperax. A structural analog of the tools – Acyclovir. It is not recommended to pick their own peers.

    Consider some analogues read more:

    • Acyclovir – cheap counterpart. The drug is produced in form of tablets, ophthalmic ointment, topical cream, and of a lyophilisate for preparation of solution. Not prescribed on the background of organic intolerance of the active substance in adults and children. Tablets do not give to children under 2 years. With caution is prescribed on the background of neurological disorders, disorders of kidney function;
    • Cyclovir – drug antiviral properties. Available in the form of tablets for internal use and cream. The latter option is used for the treatment of very young children; tablets do not give to children under the age of 2 years.

    Described medications can be a complete substitute for Zovirax. Correction of the assignments required in the development of allergic reactions to the occurrence. anxiety symptoms.

    Zovirax is an antiviral medication that has several medicinal forms. Most often prescribed for the treatment of chickenpox in children, shingles and herpes in adults. Cream and ointment in 99% of cases well tolerated, pills occasionally lead to the development of negative phenomena.

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