The vaccine against human papilloma virus and HPV vaccination

The types and descriptions of vaccines against human papilloma virus human

It is proved that 70 % of cancers of the uterine cervix (cervical cancer) caused by the human papillomavirus. There are several known oncogenic and most dangerous strains of this infection. Virus 18, 11, 16 and 6 types. Some of them cause cervical cancer, other anogenital condylomas, which can degenerate malignant. Currently the most reliable protection against these types of infection is vaccination against HPV. In our country, the using 2 types of vaccines: the drug Gardasil and Cervarix tool. Consider the features of their use, indications and contraindications in detail.

  • The Vaccine Gardasil
  • Testimony
  • Contraindications
  • Application
  • Adverse reactions
  • Cervarix
  • Testimony
  • Application features
  • Side effects
  • Contraindications

The Vaccine Gardasil

This HPV vaccination contains the following recombinant antigens:

  • protein of HPV type 6 – 20 mg;
  • 11 type 40 mcg;
  • Type 16 – 40 mg;
  • 18 type – 20 mcg.

One dose (0.5 ml) contains the following auxiliary ingredients:

  • the hydroxyphosphate sulfate aluminum amorphous;
  • sodium chloride;
  • histidine;
  • sodium borate;
  • Polysorbate 80;
  • the injection water.

It is a white opaque suspension. The vaccination against HPV does not contain the whole DNA viruses, following vaccination, eliminated the infection of cells, the reproduction of the virus and the disease.

Important! If you are interested in how much the vaccine, its price is within 100 $.


Shots of HPV vaccine Gardasil to girls and women starting from the age of nine to 45 years. Gardasil is needed to prevent diseases caused by viruses 11, 6, 18, and 16 types, including cervical cancer, vulvar cancer, anal canal, vagina, and dysplastic and precancerous lesions, and other abnormalities, HPV, and genital warts.

HPV vaccine administered to girls starting from the age of 9 to 26 years to prevent cervical intraepithelial neoplasia, which is associated with viruses 33, 31, 58 and 52 varieties, as well as adenocarcinoma uterine cervix.

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The vaccine against papilloma virus administered to boys and men starting from the age of nine and 26 years for prevention of diseases caused by oncogenic HPV, namely:

  • a vaccine against anal cancer stroke, caused by a virus 16 and 18 varieties;
  • HPV injections genital warts, which are formed due to infection of HPV 11 and 6 species.

Vaccination against papillomavirus in men is to prevent dysplastic and precancerous lesions provoked by oncogenic strains of the infection.


Vaccination against HPV vaccine Gardasil is contraindicated in case of hypersensitivity to ingredients of the preparation. The vaccination against the papilloma is contraindicated in severe allergic reactions to yeast.

Since vaccination is carried out in several stages, if, after introduction of the vaccine against human papilloma virus appeared a hypersensitivity reaction, further doses of refuse.

Vaccination against HPV Gardasil is delayed in such cases:

  • various infection and diseases in the acute stage;
  • fever.

Attention! In the presence of a subfebrile temperature in the background light infections of the upper respiratory system against vaccination did not need to.


To be vaccinated only if you have a set for emergency treatment for the development of the reaction anaphylactic shock. If there is a reaction to the vaccine providers should observe the patient for another half an hour.

The vaccination scheme is the following:

  • Children from nine years old to 13 years administered two doses (0.5 ml each), and the second is vaccination doing in six months. If the second vaccine is given until six months have passed, then make the third shot. You can use trandatebuy the vaccination: the first dose at 0 months, the second one 1-2 months later, 3rd – a minimum of 3 m after the 2nd or six months after the beginning of vaccination. All injections must be made for one year.
  • Vaccination against human papillomavirus for children over the age of 14 and adults do trendovi scheme as described above.
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    Adverse reactions

    As for adverse reactions, it was observed the following undesirable phenomena:

  • The lymphatic system and blood: lymphadenopathy, idiopathic purpura, autoimmune anemia.
  • Immune system: anaphylactic reaction and hypersensitivity.
  • Nervous system: headache, dizziness quite often.
  • Gastrointestinal tract: vomiting, nausea.
  • Musculoskeletal system: myalgia, artralgia, pain in the limbs.
  • Local and General reactions: swelling, pain, itching, hematoma, fever, weakness, chills, asthenia and malaise.
  • Cervarix

    The vaccine against human papilloma virus Cervarix is composed of the following components:

    • proteins of HPV varieties 16 – 20 g;
    • virus 18 varieties – 20 mcg.

    In addition, the composition of the vaccine is of subsidiary ingredients. As for the cost, it is in the range of 20-23 $. This recombinant adsorbed vaccine against papillomavirus is the prevention from diseases arising on a background of HPV infection.


    Vaccination against human papilloma virus be intended to prevent cervical cancer in women and girls starting from the age of 10 and 25 years. In addition, the vaccine against human papillomavirus prescribed to patients for the prevention of such ailments:

  • Acute and chronic pathologies arising in the background of HPV;
  • Cellular pathology of unknown origin;
  • Cervical intraepithelial neoplasia;
  • Precancerous lesions resulting from infection with oncogenic strains of HPV in patients starting from the age of 10 and 25 years.
  • Application features

    For the prevention of human papillomavirus, the vaccine is administered intramuscularly. Strictly contraindicated subcutaneous or intravenous administration of the vaccine. Flu vaccine is available on prescription infectious diseases. Before the introduction of the syringe with dose shaken to obtain a homogeneous white suspension.

    Vaccination against human papillomavirus is done in three stages:

  • First time introduces a single drug dose, namely 0.5 ml.
  • After a month re-injected the same dose of Cervarix.
  • After 6 months from start of vaccination is the introduction of the third dose.
  • There is no information regarding revaccination. Vaccination is performed only in a medical facility. Because immediately after the injection may cause hypersensitivity reactions or anaphylactic shock, the first few minutes of the medical staff should monitor the condition of the patient.

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    Side effects

    You may experience the following complications from vaccination:

    • it was noted the reactions of the nervous system such as headache, fatigue and dizziness;
    • from the digestive tract occasionally observed nausea, abdominal pain, vomiting, problems with the chair;
    • musculoskeletal system: myasthenia gravis, pain in the muscles;
    • skin reactions: itching, urticaria;
    • other side effects: hyperthermia, respiratory system infection, induration or swelling at the injection site, itching, decrease of local sensitivity.


    Vaccination against the human papilloma virus vaccine Cervarix is contraindicated in patients with hypersensitivity to some ingredients. The vaccine may not be performed in hyperthermic conditions, including such conditions arise on the background of aggravation of chronic illnesses.

    Important! With extreme caution vaccinations in patients with abnormalities of the hemopoietic system and thrombocytopenia.

    The drug is not intended for the treatment of ailments caused by human papilloma viruses, namely their 18 and 16 species that are already present in the body at the time of vaccination. After the administration of funds is not contraindicated to drive a car, but it is necessary in each case to assess the condition of the patient.

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