Ruppin — instructions for use and aesthetics

Roofin from allergies: instructions for use

For the treatment of various diseases of allergic origin doctors often use the drug Ruppin. This medicine 2nd generation antihistamine drugs. Our article will detail instructions for use of the drug, analogues of Ruppin, its contraindications and side effects.

  • Pharmacological effect and release form
  • Instructions for use and composition
  • Side effects
  • Method of application and doses
  • Analogues of the drug

Pharmacological effect and release form

If you have appointed Ruppin what this drug is, it is possible to learn from the instruction. This is a selective and long-acting blocker of H1-histamine receptors (peripheral). Metabolites Ruppina (trihydroxybenzoate and desloratadin) can save their antiallergic properties, and to increase the effectiveness of therapy.

Ruppin in high concentration can suppress degranulation activity of fat cells, which is not provoked by immunological and immunological stimuli. Also, the drug suppresses the concentration of neutrophils and eosinophils. It contributes to the silencing of adhesion of neutrophils.

When using therapeutic doses of the drug in the amount of 10-20 mg per day is not marked negative impact on the Central nervous system. In the treatment of various types of urticaria medication can quickly reduce the severity of symptoms.

The drug is available in tablets only. Photo of a medicine in a network may differ depending on manufacturer. Pills Rumafen rapidly absorbed after ingestion and is used against allergies.

Instructions for use and composition

Indications for use of medications – Ruppin is prescribed for symptomatic treatment of hay fever, perennial allergic rhinitis and symptoms of urticaria in adults and children over the age of twelve.

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The main active ingredient of the drug Ruppin – rupatadine fumarate. One pill contains of 12.8 milligrams the main ingredient, which is equal to 10 mg of rupatadine. Part medications include the following additional components:

  • corn starch;
  • red iron oxide;
  • microcrystalline cellulose;
  • yellow iron oxide;
  • magnesium stearate;
  • lactose.

Interaction with other medicinal products and foods:

  • Together with erythromycin and ketoconazole increased systemic exposure Ruppina ten times. Thus, the systemic impact of erythromycin and ketoconazole increased threefold. But the frequency of adverse reactions is not increased.
  • It is not necessary to wash down the drug with grapefruit juice because it increases the General effect of medications.
  • Ruppin in a dosage of 20 mg in combination with ethanol can increase the changes that alcohol causes in the human body.
  • This drug should not be used in conjunction with statins, due to the increasing levels of CPK.
  • Side effects

    When using the drug were noted such side effects:

  • Invasion and infection: rarely on the background of a rhinitis and pharyngitis.
  • Nutrition and metabolism: decreased appetite.
  • Central nervous system: often patients are faced with a headache, drowsiness and dizziness. Less frequently had impaired attention.
  • Respiratory system: cough, dry nasal mucosa, epistaxis, pain and dryness in throat and larynx.
  • The digestive system: often patients are faced with dryness in the mouth, less any abdominal pain, vomiting, dyspepsia, constipation.
  • Skin: rarely noted the appearance of the rash.
  • Musculoskeletal system: may cause myalgia, arthralgia, and less frequently pain in the back.
  • Other reactions: asthenia, fatigue, malaise, thirst, irritation and fever.
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    Contraindications to the use of medications Ruppin:

    • liver and kidney failure;
    • the period of waiting for a baby;
    • breastfeeding;
    • not indicated for children under the age of twelve;
    • hypersensitivity to the drug;
    • deficiency of lactose, galactose intolerance hereditary, and the syndrome of inadequate intake of galactose-glucose.

    Method of application and doses

    If you have appointed Ruppin, instructions for use contains accurate and detailed information about the dosage and method of medication. For the treatment of adolescents over the age of twelve and adults used one tablet per day, which is equal to the dose of the drug 10 mg. Pill drink regardless of eating.

    With caution the drug is prescribed for the treatment of elderly patients (over 65 years). Usually does not require correction doses of the drug, but it is important the supervision of a physician. Also Ruppin caution appoint patients with uncorrected hypokalemia, prolonged QT interval, proaritmicski States (acute ischemia, bradycardia).

    Since the use of modern antihistamines are not observed reactions on the Central nervous system, contraindications to management of mechanisms and cars. But as some testimonials contain information on the sleepiness that was observed during therapy Ruppina, you should be very careful while driving a car and operating machinery to identify the individual response of the nervous system this medicine.

    Analogues of the drug

    With regard to structural analogs of the drug on the active substance, they do not. If you pick up the analogs in the pharmacological group, you can find a lot of inexpensive analogues:

    • Allergodil;
    • Gestagen;
    • I suffered;
    • Desloratadin;
    • Gifast;
    • Diphenhydramine;
    • Zodak;
    • Zyrtec;
    • Claritin;
    • Lomilan;
    • Loratadine;
    • Tavegil;
    • Suprastin;
    • Fenistil;
    • Fenkarol;
    • Effective;
    • Eurespal;
    • Aerius.
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    If we talk about which of these medicines cheaper, it Diphenhydramine and loratadine. However, if you choose among the cheapest analogs, it is better to give preference to Loratadine, since Diphenhydramine has a depressant effect on the Central nervous system and causes severe drowsiness.

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