Metrogyl gel: instructions for use for the face and in gynecology
Drug Metrogyl: method of issuance and application
For the treatment of various infections of the skin and mucous shows the use of local antibiotic and antifungal drugs. The application of Metrogyl gel in gynecology due to the high antibacterial activity of the drug and its ability to destroy fungal organisms. The special composition allows its use for effective treatment of thrush. The medicine is also prescribed for the treatment of this disease in men. The drug is Metrogyl available in different forms. It is administered intravenously, used for the local treatment of skin diseases and other infectious diseases.
- Method of production and composition
- Ointment Metrogyl
- Application and contraindications
- Adverse reactions
- Vaginal gel
- Indications and applications
- Contraindications and side effects
- A Solution Of Metrogyl
- Adverse reactions and contraindications
- The reviews about the drug
Method of production and composition
Medication Metrogyl is available in gel form for external use, ointments for intravaginal use, in the form of oral tablets and solutions for injection intravenously. The composition of each form of this medication is the main active ingredient is metronidazole. The gel and ointment and 10 mg of main substance, in a solution of 5 mg. depending on the method of production of drugs in its composition auxiliary components. As for gel, it is:
- sodium hydroxide;
- methyl parahydroxybenzoate;
- karbomer 940;
- edetate disodium;
- propylene glycol.
Metrogyl gel is a smooth cream whitish to yellowish in color with characteristic odor. Vaginal gel Metrogyl 1 % comes in a tube with a volume of 30 ml, complete with applicator for easier administration of the medicine.
For the treatment of diseases of the skin and mucous membranes you can use the following analogs of this drug: Trichopolum, Metronidazole-AKOS, Rozeks, Glaygl, Metrogil Denta, Klion, Metronidazole, Rosamet. However, reviews say that herbal medicine is much more effective.
Metrogyl ointment is Antiprotozoal and antimicrobial drugs belonging to the group of imidazoles and has a wide spectrum of effects on pathogenic microorganisms. It is active against many anaerobes and protozoa.
In the local treatment of the skin having protivopravnoy impact. This is due to the influence of the drug on production of the sebaceous glands. Effective not only acne, it has antioxidant activity. This helps to reduce damage to the tissues located at the site of inflammation.
When you use ointment Metrogyl practically not absorbed into the bloodstream, which tracks only traces of the drug. Gel for external use are prescribed in such cases:
Application and contraindications
Contraindications include hypersensitivity to certain ingredients drug medications. With caution Metrogyl gel for acne prescribed for treatment of pregnant women in the first trimester and during breastfeeding, because the drug is able to penetrate through the placenta.
For persons Metrogyl apply on clean skin. Ointment applied in a thin layer twice a day during the 21-63 days. Can be used under an occlusive dressing. Typically, the duration of therapy up to 4 months. If you use Metrogyl gel for the face, the first effect of its application will be visible after 21 days of continuous therapy.
Because of Metrogyl plus gel is practically not absorbed into the bloodstream, systemic side effects are absent. However, in the brand drug is Metrogyl instruction manual, which says that occasionally there are allergic reactions manifested by skin rash and hives. You may also see the following local adverse reactions:
- peeling of the skin;
- burning and dryness of the skin;
- when applied near the eyes can tearing.
If you buy Metrogyl plus manual this product contains the following information about its action: the active substance inhibits the synthesis of nucleic acids in cellular DNA of microorganisms. This contributes to their death. The gel is active against protozoa microbes, anaerobic bacteria, including spore-forming and nonspore, and also against gram-positive microorganisms.
Endovaginal after the introduction of the active substance partially absorbs into the bloodstream and is detected in plasma at a maximum concentration of 2 % of the total administered dose. The drug is able to penetrate through natural barriers of the human body and is excreted in breast milk. Metabolism occurs in the liver and excretion of the drug is via the kidneys.
Indications and applications
Indications for use:
- therapy of urogenital trichomoniasis;
- medication prescribed for the treatment of vaginitis caused by microorganisms sensitive to the main active substance.
Method of application – only intravaginal. Prescribed amount of gel inserted into the vagina using the applicator. As a rule, for the treatment of these diseases using 5 g of gel, which is injected twice a day. The duration of treatment is one week.
Attention! During treatment the gel Metrogyl need to abstain from sexual contacts and treat sexual partner.
Contraindications and side effects
In the package there is a gel and instructions for use, which contains the following information about the local side effects of the drug:
- burning and itching;
- swelling and redness at the place of use;
- more frequent urination.
Among the systemic side-effects is called a change of taste, metallic taste in the mouth, vomiting, anorexia, nausea, abdominal pain, dark urine and irregular bowel movement. Sometimes there is headache, leukocytosis, dizziness, and leukopenia.
Contraindications to the use of drugs the following:
With extreme caution therapy during pregnancy (2nd and 3rd trimenon), in patients with liver failure and informed the transferred radiation.
A Solution Of Metrogyl
1 ml of the drug solution contains 5 mg of metronidazole. As additives the following substances: citric acid monohydrate, sodium chloride, anhydrous disodium hydrosulfite, injection water.
For the treatment of complex and advanced forms of infectious diseases are shown not only the use of local antimicrobials, and systemic therapy. This can be prescribed tablets or a dropper. Solution Metrogyl administered intravenously in such cases:
- sepsis, peritonitis, osteomyelitis;
- as part of combination therapy in the form of mixed anaerobic and aerobic infections;
- treatment and prevention of anaerobic infections during surgical operations on the system of the urinary tract and the abdominal cavity;
- gynecological infections;
- gas gangrene;
- brain abscess, pelvic abscess forming pneumonia;
- various infectious lesions of soft tissues, skin and joints;
- in radiation therapy of tumors.
Important! Intravenous drug use for severe illness or if it is impossible to use the tablet form of the medication.
The drug is administered for seven days starting volume of 0.5-1 gram intravenous drip for half an hour and continuing to inject 500 mg every 8 hours with a speed of 5 ml per minute. If necessary, the duration of therapy can increase. Supportive therapy is carried out at a dose of 0.4 g three times per day in tablet form.
Adverse reactions and contraindications
Among the side effects of the drug is as follows:
- nausea, dry mouth, loss of appetite, taste in the mouth, pain in the abdomen;
- less vomiting, diarrhea, stomatitis, and glossitis;
- dizziness, irritability, ataxia, loss of coordination, insomnia, weakness, headache, sometimes there is anxiety, less depression;
- skin reactions, fever, nasal congestion;
- leukopenia, neutropenia, thrombophlebitis;
- very rarely seizures, pancreatitis, hallucinations, confusion.
The drug is contraindicated in case of hypersensitivity, liver failure, blood disorders and lesions of the CNS, in the first trimester of pregnancy and the process of breastfeeding.
The reviews about the drug
The opinion of patients about the use of this medication in most positive. Below, we have some of them.
Michael, 36 years:
When I had thrush in my mouth, could not cure this disease, because nothing helped. The doctor prescribed me medication Metrogyl gel form. And here in a few days I completely forgot about the pain and discomfort in the mouth. Good medicine and no adverse reactions I didn’t notice.
Irina, 52 years:
Because dentures often happens I have a yeast infection in the mouth. Since it is necessary to be treated often from this sore, tried many medicines. Many had to be treated for a very long time to achieve a positive effect. And gel Metrogyl helped me for five days. All the symptoms quickly passed and I fully recovered.