Dexamethasone how to use and for what prescribed
Injections Dexamethasone : instructions for use
The human body is designed so that at times, he produces unique substances that help to cure diseases, and now we are not talking about immune cells and the hormones secreted by the adrenal cortex. These substances, called in medicine the corticosteroids. They normalize the carbon, protein metabolism, and is also able to arrest the inflammatory and allergic process at an early stage. One of the more unusual hormone is dexamethasone. Scientists, evaluating its positive qualities, began to produce a synthetic drug analogue of a natural substance, with the same name. Dexamethasone instructions for use, which comes in the kit, today, you can buy in almost every pharmacy.
- Pharmacological effect and release form
- Instructions for use and composition
- Side effects
- Method of application and doses
- Analogues of the drug
Pharmacological effect and release form
Abstract to the drug claims that the drug can prevent development of the inflammatory process, and neutralize the source of inflammation. In addition, it has antihistamine properties — inhibits the release of histamine from mast cells and eliminates particles that have already released. Dexamethasone Allergy helps to relieve symptoms such as:
- redness of the skin;
- swelling of the mucous membranes;
- burning and itching;
Dexamethasone therapy is prescribed very often, because this tool, in addition to the therapeutic effect, improves metabolic processes and accelerates the regeneration of damaged cells. Injection with solution of Dexamethasone reduces the permeability of blood vessels, eliminate swelling of the respiratory sheath and accelerates the excretion of toxic substances that could provoke an allergic reaction.
There are Dexamethasone tablets Dexamethasone in capsules and ointment Dexamethasone. Each form has its own characteristics and scope. For example, an ointment is produced in tubes of 2.5 mg, it is used for topical treatment. Dexamethasone children can be administered in tablet form, they produce 10 pieces in a mesh packages. Cardboard packaging may contain 5 blisters. Dexamethasone solution for injection is available in glass ampoules of 5 PCs.in packaging.
The strength of its aktivnosti 0.5 mg of Dexamethasone is similar to using 15 mg of Hydrocortisone, 3.5 mg of Prednisone or 17.5 mg of Cortisone, what are some of the most effective glucocorticosteroid drugs.
Instructions for use and composition
The medicine comprises the main active substance dexamethasone. As a complement, each drug has differing components. So the solution for injection, in addition to dexamethasone phosphate contains: glycerin, disodium edetate, sodium hydrogen phosphate dihydrate and water. Dexamethasone tablets as excipients, contain:
- lactose monohydrate;
- the cellulose mikrochristallicescuu;
- silicon dioxide;
- sodium croscarmelose;
- magnesium stearate.
All of these substances are perfectly absorbed in the blood and in the gastrointestinal tract. The maximum concentration observed after oral intake, after 2 hours. If the drug got into the body intramuscularly, the maximum concentration is, after 20 minutes in the blood.
Regardless, there has been an introduction of intravenous, intramuscular, or used topically, Dexamethasone is able to react with other medications. It increases toxic effect on the body glycosides, heart medications, reduces the concentration of folic acid increases the risk of activation of viruses if it is used after vaccination.
Dexamethasone what is prescribed, you can read in the instruction that always comes. In most cases, a medication used for the treatment of:
- bronchial asthma;
- spasms of smooth muscles;
- allergic conjunctivitis;
- allergic inflammation of the iris of the eye;
- allergic edema of the brain;
- shock conditions;
Injections Dexamethasone and other forms of medication that are used in allergic reactions is not able to act purposefully, after being hit in the body, they affect practically all organs and systems. For this reason, it is not necessary to appoint a cure. Only a doctor can help based on your individual characteristics, to choose the optimum dose of the drug, and will exclude the negative effect of the substance on the body.
In addition to good effects is Dexamethasone contraindications. It is forbidden to use the drug, people:
- with a personal intolerance to the active substances or components of the product;
- children up to 12 years;
- with diabetes;
- with hypothyroidism;
- survived a heart attack;
- with nephrotic syndrome;
- with devikulam;
- with ulcerative colitis;
- with gastritis.
To use ampoules of Dexamethasone in ml for injection, is strictly prohibited in the treatment of pregnant women because the active ingredient is able to penetrate the placental barrier and disrupt the normal development of the fetus in the womb. The same goes for lactation, Dexamethasone may alter the quantitative and qualitative composition of breast milk.
If you have not complied with the dosage or ignored contraindications to eat, and can develop side effects after using the medication. Most often, patients reported at:
- jumps in blood pressure;
- blurred vision;
- loss of appetite;
- stomach bleeding;
- disorders of defecation.
Against the background of misuse of this drug Allergy may develop diabetes, dysmenorrhea, amenorrhea, maybe should be suppressed by the activity of the adrenal glands, the ulcer on the stomach and delayed sexual development in adolescents.
If you have the above symptoms, immediately seek medical assistance. With proper medication, such a reaction of the body should not be.
A number of unpleasant symptoms may occur with abrupt withdrawal of the drug. The dose is reduced gradually over weeks. After injection of Dexamethasone, or taking it orally, forbidden to drive a car, as there is a possibility that when a wrong dose, can develop hallucinations and muscle spasms, which may affect the reaction ability while driving.
Method of application and doses
Medication for children shall be appointed in minimal doses with age and weight of the patient. Tablets: adults should take special scheme, which include minimal use of medication in the morning is 2-6 mg a Large dose of day — 10-15 mg and the same dose in the evening. After obtaining the optimal result, the use of medication was reduced to 0.5 mg per day. Therapy pills completed 2 injections of Corticotropin.
The drug Dexamethasone 1.0 ml which contains 4 mg of active substance to be administered intravenously or intramuscularly up to 4 times a day at 4-20 mg. Dosage the doctor selects individually. Treatment injections should not exceed 4 days. If you need continued therapy, the patient is transferred to a tablet form of medication.
Can intra-articular injections Dexamethasone directly into the inflammation at 2 to 8 mg, 1 times a day. Teenagers shown the dose from 0.2 to 6 mg. the Maximum dosage for intraarticular injection medication for adults is 80 mg per 24 hours.
It will be interesting to see what you can use ampules Dexamethasone for inhalation. The drug is in the form of steam helps to relieve spasm of the larynx, and attacks of shortness of breath, dyspnea in people with chronic bronchitis, allergic cough and asthma. It is necessary for adults to pour into the nebulizer at 1 ml, and 0.5 ml. for children to Breathe before complete evaporation, is typically 20 minutes, three times a day.
Analogues of the drug
Dexamethasone pharmacies sell prescription. If necessary, replace the drug can be analog means. They have a similar description, principle of operation and even the active substance. Among the most effective analogues of Dexamethasone include:
- This solution.
Before using these tools, carefully read the leaflet instruction, they may differ from Dexamethasone its composition, respectively, do not exclude an allergic reaction.
Reviews Dexamethasone when applied correctly, has only positive, negative comments are recorded only in people that self-medicating or ignored the dosage specified by the doctor. That’s what people say who have tested the medicine:
Valeria, 26 years:
«I don’t know what there was severe conjunctivitis. The doctor said it is allergic in nature, though I have never encountered allergic reactions. As a preparation for the treatment, I was prescribed the Dexamethasone ointment and drops. Ointment I treated swollen skin on the eyelids and under the eyes, and the drops was directly used for the mucous membrane of the eye. The medicine gave effect immediately, three days later stopped itching and burning in the eye, and five days later the swelling is completely asleep.»
Konstantin, 33 years:
«Throughout the year suffer from asthmatic bronchitis, are most afraid of asthma attacks that appear when I show excessive physical activity. To stop spasms I highly inhalation Dexametasona. Initially, he injected the drug, but then, buying a nebulizer, use a more gentle method of therapy. Despite the fact that Dexamethasone is a hormonal drug, no side effects and consequences of regular use, I do not feel. Probably doctor the right dosage, because the medicine brings me.»